This document is the user manual for the Compucorp Alpha 327 Scientist, a programmable desktop computer for scientific, mathematical, and engineering calculations. It explains how to use the computer’s keyboard, programming features, printer, and optional 392 Tape Cassette Drive. The main topics include: - Basic operation: entering numbers, setting decimal formats, performing arithmetic, using constants and parentheses, and calculating with angles. The computer uses 13 significant digits internally and provides 44 data storage registers, - Scientific functions: powers, roots, factorials, trigonometric and logarithmic functions, coordinate conversions, statistics, and conversions between metric and English units, - Programming: recording sequences of keyboard operations so calculations can run automatically. The manual covers flowcharts, labels, jumps, conditional tests, loops, and subroutines, along with tools for editing and executing programs one step at a time, - Practical examples: worked calculations and programs for projectile motion, spherical coordinates, great-circle distances, statistics, the volume of a hollow sphere, and polynomial evaluation, - Cassette storage: saving and loading programs and register data, locating tape blocks, and controlling tape operations from a program. Program overlays allow successive sections to load from tape, extending the effective capacity beyond internal memory, - Technical reference and maintenance: numerical accuracy, instruction codes, error conditions, printer paper and ribbon replacement, self-testing, operating conditions, cassette care, and peripheral connections. The manual serves both as a progressive tutorial and a reference guide, helping users move from direct keyboard calculations to automated workflows with reusable programs and stored data.